Recent Publications
Andrews PW
Hovatta O, Jaconi M, Töhönen V, Béna F, Gimelli S, Bosman A, Holm F, Wyder S, Zdobnov EM, Irion O, Andrews PW, Antonarakis SE, Zucchelli M, Kere J, Feki A.
A teratocarcinoma-like human embryonic stem cell (hESC) line and four hESC lines reveal potentially oncogenic genomic changes.
PLoS One. 2010 Apr 23;5(4):e10263.
Tonge PD, Andrews PW.
Retinoic acid directs neuronal differentiation of human pluripotent stem cell lines in a non-cell-autonomous manner.
Differentiation. 2010 Apr 26. [Epub ahead of print]
Närvä E, Autio R, Rahkonen N, Kong L, Harrison N, Kitsberg D, Borghese L, Itskovitz-Eldor J, Rasool O, Dvorak P, Hovatta O, Otonkoski T, Tuuri T, Cui W, Brüstle O, Baker D, Maltby E, Moore HD, Benvenisty N, Andrews PW, Yli-Harja O, Lahesmaa R.
High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity.
Nat Biotechnol. 2010 Apr;28(4):371-7. Epub 2010 Mar 28.
Avery S, Zafarana G, Gokhale PJ, Andrews PW.
The role of SMAD4 in human embryonic stem cell self-renewal and stem cell fate.
Stem Cells. 2010 May;28(5):863-73.
Andrews PW, Benvenisty N, Knowles BB, McKay RD, Oh SK, Pera MF, Rossant J, Stacey GN.
Human ES cell lines--introduction.
In Vitro Cell Dev Biol Anim. 2010 Apr;46(3-4):167-8. Epub 2010 Mar 7. available.
Akopian V, Andrews PW, Beil S, Benvenisty N, Brehm J, Christie M, Ford A, Fox V, Gokhale PJ, Healy L, Holm F, Hovatta O, Knowles BB, Ludwig TE, McKay RD, Miyazaki T, Nakatsuji N, Oh SK, Pera MF, Rossant J, Stacey GN, Suemori H.
Comparison of defined culture systems for feeder cell free propagation of human embryonic stem cells.
International Stem Cell Initiative Consortium,
In Vitro Cell Dev Biol Anim. 2010 Apr;46(3-4):247-58. Epub 2010 Feb 26.
Consensus guidance for banking and supply of human embryonic stem cell lines for research purposes.
International Stem Cell Banking Initiative.
Stem Cell Rev. 2009 Dec;5(4):301-14. No abstract available.
Olariu V, Harrison NJ, Coca D, Gokhale PJ, Baker D, Billings S, Kadirkamanathan V, Andrews PW.
Modeling the evolution of culture-adapted human embryonic stem cells.
Stem Cell Res. 2010 Jan;4(1):50-6. Epub 2009 Sep 16..
Moore H
Frost JM, Udayashankar R, Moore HD, Moore GE
Telomeric NAP1L4 and OSBPL5 of the KCNQ1 Cluster, and the DECORIN Gene Are Not Imprinted in Human Trophoblast Stem Cells.
PLoS One. 2010 Jul 14;5(7):e11595.PMID: 20644730 [PubMed - in process
Hemberger M, Udayashankar R, Tesar P, Moore H, Burton GJ
ELF5-enforced transcriptional networks define an epigenetically regulated trophoblast stem cell compartment in the human placenta.
Hum Mol Genet. 2010 Jun 15;19(12):2456-67. Epub 2010 Mar 30
Amps KJ, Jones M, Baker D, Moore HD.
In situ cryopreservation of human embryonic stem cells in gas-permeable membrane culture cassettes for high post-thaw yield and good manufacturing practice.
Cryobiology. 2010 Jun;60(3):344-50. Epub 2010 Mar 27
Udayashankar R, Kershaw C. and Moore H
Models of trophoblast development and embryo implantation using human embryonic stem cells. (2010).
In Stem Cells in Reproductive Medicine. Informa Heathcare Books, London
Aflatoonian B, Ruban L, Shamsuddin S, Baker D, Andrews P, Moore H.
Generation of Sheffield (Shef) human embryonic stem cell lines using a microdrop culture system.
In Vitro Cell Dev Biol Anim. 2010 Apr;46(3-4):236-41. Epub 2010 Mar 12
Suárez-Alvarez B, Rodriguez RM, Calvanese V, Blanco-Gelaz MA, Suhr ST, Ortega F, Otero J, Cibelli JB, Moore H, Fraga MF, López-Larrea C
Epigenetic mechanisms regulate MHC and antigen processing molecules in human embryonic and induced pluripotent stem cells.
PLoS One. 2010 Apr 16;5(4):e10192
Blanco-Gelaz MA, Suarez-Alvarez B, Ligero G, Sanchez L, Vidal-Castiñeira JR, Coto E, Moore H, Menendez P, Lopez-Larrea C.
Endoplasmic Reticulum Stress Signals in Defined Human Embryonic Stem Cell Lines and Culture Conditions.
Stem Cell Rev. 2010 Mar 30. [Epub ahead of print]
Närvä E, Autio R, Rahkonen N, Kong L, Harrison N, Kitsberg D, Borghese L, Itskovitz-Eldor J, Rasool O, Dvorak P, Hovatta O, Otonkoski T, Tuuri T, Cui W, Brüstle O, Baker D, Maltby E, Moore HD, Benvenisty N, Andrews PW, Yli-Harja O, Lahesmaa R.
High-resolution DNA analysis of human embryonic stem cell lines reveals culture-induced copy number changes and loss of heterozygosity.
Nat Biotechnol. 2010 Apr;28(4):371-7. Epub 2010 Mar 28.
Aflatoonian B, Ruban L, Jones M, Aflatoonian R, Fazeli A, Moore HD
In vitro post-meiotic germ cell development from human embryonic stem cells.
Hum Reprod. 2009 Dec;24(12):3150-9. Epub 2009 Sep 20.
Sonne SB, Almstrup K, Dalgaard M, Juncker AS, Edsgard D, Ruban L, Harrison NJ, Schwager C, Abdollahi A, Huber PE, Brunak S, Gjerdrum LM, Moore HD, Andrews PW, Skakkebaek NE, Meyts ER, Leffers H.
Analysis of Gene Expression Profiles of Microdissected Cell Populations Indicates that Testicular Carcinoma In situ Is an Arrested Gonocyte.
Cancer Res. 2009 Jun 15;69(12):5241-50. Epub 2009 Jun 2.
Timmermans F, Velghe I, Vanwalleghem L, De Smedt M, Van Coppernolle S, Taghon T, Moore HD, Leclercq G, Langerak AW, Kerre T, Plum J, Vandekerckhove B.
Generation of T cells from human embryonic stem cell-derived hematopoietic zones.
J Immunol. 2009 Jun 1;182(11):6879-88.
Chen W, Johnson SL, Marcotti W, Andrews PW, Moore HD, Rivolta MN.Stem Cells.
Human fetal auditory stem cells can be expanded in vitro and differentiate into functional auditory neurons and hair cell-like cells.
2009 May;27(5):1196-204.PMID: 19418454 [PubMed - indexed for MEDLINE
Carr AJ, Vugler A, Lawrence J, Chen LL, Ahmado A, Chen FK, Semo M, Gias C, da Cruz L, Moore HD, Walsh J, Coffey PJ.
Molecular characterization and functional analysis of phagocytosis by human embryonic stem cell-derived RPE cells using a novel human retinal assay.
Mol Vis. 2009;15:283-95. Epub 2009 Feb 6
Zafarana G, Avery SR, Avery K, Moore HD, Andrews PW.
Specific knockdown of OCT4 in human embryonic stem cells by inducible short hairpin RNA interference.
Stem Cells. 2009 Apr;27(4):776-82
Rivolta M
Jongkamonwiwat N, Zine A, Rivolta MN.
Stem cell based therapy in the inner ear: appropriate donor cell types and routes for transplantation.
Curr Drug Targets. 2010 Jul;11(7):888-97.
Rivolta MN.
Stem cells and cell lines from the human auditory organ: applications, hurdles and bottlenecks in the development of regenerative therapies for deafness.
Drug Discov Today. 2010 Apr;15(7-8):283-6. Epub 2010 Feb 25.
Johnson SL, Franz C, Kuhn S, Furness DN, Rüttiger L, Münkner S, Rivolta MN, Seward EP, Herschman HR, Engel J, Knipper M and Marcotti W (2010)
Synaptotagmin IV determines the linear calcium dependence of vesicle fusion at auditory ribbon synapses.
Nature Neurosci 2010 Jan;13(1):45-52.
Milo M, Cacciabue-Rivolta D, Kneebone A, Van Doorninck H, Johnson C, Lawoko-Kerali G, Niranjan M, Rivolta M, Holley M.
Genomic analysis of the function of the transcription factor gata3 during development of the mammalian inner ear.
PLoS One. 2009 Sep 23;4(9):e7144.
Objoon, T and Rivolta, M.N.
Neural differentiation of human embryonic stem cells and their potential application in a therapy for sensorineural hearing loss.
In Trends in Stem Cell Biology and Technology (Baharvand H ed) Humana Press, pp 261-282, 2009.
Chen W, Johnson SL, Marcotti W, Andrews PW, Moore HD, Rivolta MN.
Human fetal auditory stem cells can be expanded in vitro and differentiate into functional auditory neurons and hair cell-like cells.
Stem Cells. 2009, 27:1196-204.
Taylor V
Lugert S, Basak O, Knuckles P, Haussler U, Fabel K, Götz M, Haas CA, Kempermann G, Taylor V, Giachino C.
Quiescent and active hippocampal neural stem cells with distinct morphologies respond selectively to physiological and pathological stimuli and aging.
Cell Stem Cell. 2010 May 7;6(5):445-56.
Onichtchouk D, Geier F, Polok B, Messerschmidt DM, Mössner R, Wendik B, Song S, Taylor V, Timmer J, Driever W.
Zebrafish Pou5f1-dependent transcriptional networks in temporal control of early development.
Mol Syst Biol. 2010;6:354. Epub 2010 Mar 9.
Favaro R, Valotta M, Ferri AL, Latorre E, Mariani J, Giachino C, Lancini C, Tosetti V, Ottolenghi S, Taylor V, Nicolis SK.
Hippocampal development and neural stem cell maintenance require Sox2-dependent regulation of Shh.
Nat Neurosci. 2009 Oct;12(10):1248-56. Epub 2009 Sep 6.
Sibbe M, Förster E, Basak O, Taylor V, Frotscher M.
Reelin and Notch1 cooperate in the development of the dentate gyrus.
J Neurosci. 2009 Jul 1;29(26):8578-85.
Giachino C, Taylor V.
Lineage analysis of quiescent regenerative stem cells in the adult brain by genetic labelling reveals spatially restricted neurogenic niches in the olfactory bulb.
Eur J Neurosci. 2009 Jul;30(1):9-24. Epub 2009 Jun 25.
Hartman BH, Basak O, Nelson BR, Taylor V, Bermingham-McDonogh O, Reh TA.
Hes5 expression in the postnatal and adult mouse inner ear and the drug-damaged cochlea.
J Assoc Res Otolaryngol. 2009 Sep;10(3):321-40. Epub 2009 Apr 17.
Jolly LA, Taylor V, Wood SA.
USP9X enhances the polarity and self-renewal of embryonic stem cell-derived neural progenitors.
Mol Biol Cell. 2009 Apr;20(7):2015-29. Epub 2009 Jan 28.
Neumeister B, Grabosch A, Basak O, Kemler R, Taylor V.
Neural progenitors of the postnatal and adult mouse forebrain retain the ability to self-replicate, form neurospheres, and undergo multipotent differentiation in vivo.
Stem Cells. 2009 Mar;27(3):714-23.
Giachino C, Basak O, Taylor V.
Isolation and manipulation of mammalian neural stem cells in vitro.
Methods Mol Biol. 2009;482:143-58.
Basak O, Taylor V.
Stem cells of the adult mammalian brain and their niche.
Cell Mol Life Sci. 2009 Mar;66(6):1057-72. Review.
