Clinical Grade Stem Cells & Germ Cells

Prof Harry Moore - Principle Investigator

The CSCB is generating and characterising new embryonic stem cell lines for clinical applications. This involves the production of clinical grade cell lines and master cell banks that can meet the stringent requirements of healthcare regulators. New technologies to increase efficiency are tested and the pluripotent capacity of different cell lines evaluated.  We are also investigating gamete (sperm and egg) and trophoblast (placental) stem cells.

Group members:

Miss Katie Amps

Research Assistant

Developing new cryopreservation techniques for stem cells. Ensures that cell lines are of the correct quality and free of any contaminants. Trains new staff and visitors in the culture of embryonic stem cells.

Email: K.Amps@sheffield.ac.uk

Miss Gemma Bray

Cell Production Team Leader

Manages the production of clinical grade cell lines in our Stem Cell Derivation Facility. This involves the creation of master stem cell banks which will be used for cell therapies for many years to come.

Email: G.Bray@sheffield.ac.uk

Miss Gemma Cleaver

Cell Production Assistant

Producing clinical grade stem cell lines and developing new technologies to increase efficiency.

Email: g.cleaver@sheffield.ac.uk

Dr Zoe Hewitt

Quality Assurance Manager

Implements and manages all the processes and procedures required to produce our embryonic stem cell lines to a clinical standard. As a Designated Individual Zoe is responsible for ensuring the cells meet the stringent criteria of the Human Tissue Authority.

Email: Z.Hewitt@sheffield.ac.uk

Mr Dean Owen

 Postgraduate student

Investigating the development of retinal cells from pluripotent stem cells for the treatment of blindness. (supported by the BBSRC)

Email: c.owen@sheffield.ac.uk

Miss Heather Spink

Quality Team Leader

Ensures that clinical grade cell lines are produced to high quality and free of any contaminants.

Email: H.Spink@sheffield.ac.uk

Mr Richard Weightman

Cell Production Assistant

Producing clinical grade stem cell lines and developing new technologies to increase efficiency.

Email: r.weightman@sheffield.ac.uk

Mr Andrew Wood

Quality Assistant

Assists in ensuring clinical grade cell lines are produced to high quality and free of any contaminants.

Email: Andy.Wood@sheffield.ac.uk